The Journal of Liquid Biopsy

Analytical and clinical validation of a novel CE-IVD kit for PIK3CA hotspot mutations in liquid biopsy samples

Pub Date : 2026-03-01 DOI: 10.1016/j.jlb.2026.100458 Dimitra Stergiopoulou , Stavroula Smilkou , Elena Tzanikou , Loukas Kaklamanis , Vassilis Georgoulias , Ioanna Koukli , Athina Markou , Evi Lianidou

Cell-free RNA profiling uncovers non-canonical circulating D2 transcript elevation in Bladder Cancer plasma

Pub Date : 2026-03-01 DOI: 10.1016/j.jlb.2025.100454 Annarita Nappi , Felice Crocetto , Paolo Conforti , Serena Sagliocchi , Annunziata Gaetana Cicatiello , Federica Restolfer , Lucia Acampora , Silvia Del Mastro , Rosa Sirica , Lorenzo Spirito , Francesco Del Giudice , Roberto La Rocca , Daniela Terracciano , Monica Dentice , Caterina Miro

End-repair causes methylation underestimation in cell-free DNA sequencing libraries

Pub Date : 2026-03-01 DOI: 10.1016/j.jlb.2026.100455 Tobin E. Groth, Andrew A. Mishin, Varsha Rao, Ruby Tibet, Christopher J. Troll