Pharmaceutical Science Advances

Artificial intelligence in human immunodeficiency virus mutation prediction and drug design: Advancing personalized treatment and prevention

Pub Date : 2025-06-26 DOI: 10.1016/j.pscia.2025.100080 Karamot O. Oyediran , Peace-Ofonabasi O. Bassey , Deborah A. Ogundemuren , Abdullahi Abdulraheem , Chukwuemeka P. Azubuike , Andrew N. Amenaghawon , Margaret O. Ilomunaya

Artificial neural network guided optimization of tenofovir and Cyanovirin-N multipurpose preventive hydrogel formulation developed using the Box Behnken design model

Pub Date : 2025-06-21 DOI: 10.1016/j.pscia.2025.100079 Karamot O. Oyediran , Ibilola M. Cardoso-Daodu , Peace Ofonabasi Bassey , Deborah A. Ogundemuren , Ridwan Muhammed , Olusola E. Ojo , Andrew N. Amenaghawon , Chukwuemeka P. Azubuike , Rachna Agarwal , Kondoru Haritha , Margaret O. Ilomunaya

Study on the CHJ01 antitumor activity and mechanism via targeting sphingosine kinase 1 in A549 cells

Pub Date : 2025-05-26 DOI: 10.1016/j.pscia.2025.100077 Caiyu Liu , Shengmei Gao , Bo Liu , Feipeng Zhang , Yanling Mu , Fuwen Wang , Yan Li