Highly Enantioselective Synthesis of Chiral Hydrocarbazole-4-Carbaldehyde Scaffolds and Constrained Analogue of MS-245 via Iminium Catalysis at Elevated Temperatures.

已完结 10 由小林发布于 2026/4/16 10:02:15

DOI:10.1021/acs.orglett.6c00950
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acs.orglett.6c00950

American Chemical Society (ACS)

Abstract：The chiral hydrocarbazole-4-carbaldehyde scaffold is a privileged structural motif present in numerous biologically active indole alkaloids. Nevertheless, catalytic asymmetric access to this

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