Development of Water-Trapping Pyrrole-2-carboxylic Acids as Broad-Spectrum Metallo-β-lactamase Inhibitors.

已完结 10 由 phoebe9203 发布于 2026/5/18 9:05:00

DOI:10.1021/acs.jmedchem.5c03534
作者：Monisha Singha, Liam A Wilson, Elisabete C C M Moura, Maria M Trush, Karina Calvopina, Gurleen Kaur, Greta Zaborskyt?, Toms Kalni??, Tharindi Panduwawala, 
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Use of the clinically vital β-lactam antibiotics is increasingly compromised by resistance, commonly mediated by β-lactamases. While clinically used serine-β-lactamase (SBL) inhibitors have

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