Use of Impinging Jet to Improve Scalability in the Preparation of the ABBV-154 Drug-Linker

已完结 10 由 bro，帮帮忙发布于 2026/5/22 16:07:44

DOI:10.1021/acs.oprd.4c00143
作者：Nathan B. Bennett*,?Laurie B. Mlinar,?Eric G. Moschetta,?Ryan G. Ellis,?Ryan Chung,?Onkar Manjrekar,?Michael Rasmussen,?Laura A. McKee,?Mark A. Servos,?Justin A. Simanis,?Bradley D. Gates,?Xiaoqiang S
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：The final step in the preparation of the ABBV-154 drug-linker is a global acidic deprotection of three tert-butyl protecting groups that proceeds through several intermediates and is complic

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