Scalable total synthesis of saxitoxin and related natural products

已完结 10 由 dddd 发布于 2026/10/13 15:34:07

DOI:10.1038/s41586-025-09551-5
作者：Yinliang Guo,?Yiheng Li,?Sihan Chen,?Yige Wu,?Oscar Poll,?Zhouyang Ren,?Zhonglin Liu,?Roman Vlkolinsky,?Michal Bajo,?Christopher K. Prier,?Kai-Jiong Xiao,?Benjamin F. Cravatt,?Marisa Roberto,?Phil S.
文献类型：期刊论文
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Nature

Abstract：Saxitoxin (STX, 1), a potent neurotoxin from shellfish, first isolated in 1957 (ref. 1), offers immense pharmaceutical potential owing to its interaction with voltage-gated sodium channels2,

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