Lipid nanoparticle composition directs systemic trafficking and tissue-specific T cell immunity after intramuscular injection.

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DOI:10.1038/s41551-026-01706-7
作者：Christine Wei,?Yining Zhu,?Xiaoya Lu,?Kailei D Goodier,?Di Yu,?Xiang Liu,?Joseph Choy,?Alejandro Téllez Calderón,?Yunhe Su,?Jingyao Ma,?Jinghan Lin,?Shuyi Li,?Jonathan P Schneck,?Sean C Murphy,?Hai-
文献类型：期刊论文
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Nature

Abstract：Messenger RNA lipid nanoparticles are promising vaccine carriers, yet their movement through the body after intramuscular injection and the resulting tissue-specific immune effects remain po

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