CAR-macrophage therapy for HER2-overexpressing advanced solid tumors: a phase 1 trial

已完结 10 由 Faye 发布于 2026/5/26 14:54:32

DOI:10.1038/s41591-025-03495-z
作者：Kim A. Reiss, Mathew G. Angelos, E. Claire Dees, Yuan Yuan, Naoto T. Ueno, Paula R. Pohlmann, Melissa L. Johnson, Joseph Chao, Olga Shestova, Jonathan S. S
文献类型：期刊论文
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Nature

Abstract：Chimeric antigen receptor (CAR) macrophages (CAR-Ms) mediate antitumor immunity via phagocytosis, cytokine release, activation of the tumor microenvironment and antigen presentation. We repo

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