Development of a highly functional thermostable D-amino acid oxidase for efficient L-phosphinothricin biosynthesis using ProteinMPNN-guided engineering

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DOI:10.1016/j.ijbiomac.2025.149737
作者：Kai Yang, Yueshan Huang, Liyi Yao, Bin Huang, Weimin Zeng, Jin Huang
文献类型：期刊论文
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Elsevier

Abstract：D-amino acid oxidase (DAAO) has long been recognized as a promising catalyst for chiral amino acid biosynthesis owing to its pronounced stereospecificity. However, its limited thermostabilit

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