Skeletal editing by iron-catalyzed carbene insertion of trichloromethanes

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DOI:10.1016/j.chempr.2026.102968
作者：Bethany M. DeMuynck,?Ethan E. Hyland,?Hojin Kim,?Victoria L. Menches,?Anna M.M. Vernier,?Zhang Wang,?David E. Olson,?Mark D. Levin,?David A. Nagib
文献类型：期刊论文
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Elsevier

Abstract：Direct interchange between five- and six-membered nitrogen heterocycles by skeletal editing is valuable in drug discovery. Specifically, inserting a carbon atom into oxidatively prone indole

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