Metabolism and excretion of the once-daily human glucagon-like peptide-1 analog liraglutide in healthy male subjects and its in vitro degradation by dipeptidyl peptidase IV and neutral endopeptidase.

已完结 10 由 YAN 发布于 2026/5/28 10:04:52

DOI:10.1124/dmd.110.034066
作者：Monika Malm-Erjef?lt,?Inga Bj?rnsdottir,?Jan Vanggaard,?Hans Helleberg,?Uffe Larsen,?Berend Oosterhuis,?Jan Jaap van Lier,?Milan Zdravkovic,?Anette K Olsen
文献类型：期刊论文
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Elsevier

Abstract：Liraglutide is a novel once-daily human glucagon-like peptide (GLP)-1 analog in clinical use for the treatment of type 2 diabetes. To study metabolism and excretion of [(3)H]liraglutide, a s

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