Synergistic viral inactivation platform: Rapid enveloped virus inactivation at mildly acidic pH using low non-ionic detergent in Protein A eluates.

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DOI:10.1002/btpr.88549
作者：June X Zou,?Janice H Lee,?Shengjiang Shawn Liu,?Hendri Tjandra
文献类型：期刊论文
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Abstract：Low-pH viral inactivation (LPVI) is a widely used, validated unit operation for enveloped virus clearance in antibody manufacturing. However, acid exposure during Protein A (ProA) elution an

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