Retargeted serine integrases for one-step, precise integration of large DNA sequences in human cells.

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DOI:10.1038/s41587-026-03186-1
作者：Friedrich Fauser,Sebastian Arangundy-Franklin,Jessica E Davis,Lifeng Liu,Nicola J Schmidt,Luis Rodriguez,Danny F Xia,Nga Nguyen,Yuanyue Zhou,Nicholas A Scarlott,Lynn N Truong,Rakshaa Mureli,Irene S Ta
文献类型：期刊论文
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Nature

Abstract：Serine integrases can precisely integrate large DNA constructs into desired chromosomal sites but only if their natural target site is first installed into the recipient genome. Here, to ret

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