pTα enhances mRNA translation and potentiates CAR T cells for solid tumor eradication

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DOI:10.1016/j.cell.2025.11.005
作者：Yuzhe Shi, Michael A. Lopez, Ivan S. Kotchetkov, Nayan Jain, Zeguo Zhao, Leena Halim, Anton Dobrin, Karlo Perica, Sophie A. Hanina, Vinagolu K. Rajasekhar, Michael G. Kharas, Michel Sadelain
文献类型：期刊论文
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Elsevier

Abstract：Current chimeric antigen receptor (CAR) therapies are effective against a range of hematological malignancies and autoimmune disorders but have shown limited activity against solid tumors. I

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