Sulfonic Acid Promoted N-Boc-, N-Cbz-, and N-PMB Cleavage in 1,1,1,3,3,3-Hexafluoro-2-Propanol (HFIP) and Application to Acid Sensitive Substrates

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DOI:10.1021/acs.joc.5c02406
作者：Eddie X. Yang,?Amanda Pecora,?Ethan L. Fisher,?Christopher W. am Ende and John M. Humphrey*,?
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：We report on the mild, sulfonic acid promoted removal of N-Boc, N-Cbz, and N-PMB protecting groups in 1,1,1,3,3,3-hexafluoro-2-propanol (hexafluoroisopropanol; HFIP). According to this metho

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