From Bench to Pilot Plant: Ni-Catalyzed Negishi Reaction toward a Challenging Aminopyridine Intermediate

已完结 10 由 fengpeng 发布于 2026/11/5 13:12:04

DOI:10.1021/acs.oprd.5c00503
作者：Nana Kim*,?, ,?Matthew V. Joannou*,?, ,?Kira Ragazzo,?, ,?William P. Gallagher,?, ,?Eric M. Saurer,?, and ,?Thomas E. La Cruz,?
文献类型：期刊论文
补充材料：只需要正文

American Chemical Society (ACS)

Abstract：The reaction development, process optimization, and pilot plant production of a key intermediate in the synthesis of Afimetoran (BMS-986256) are reported. A convergent Ni-catalyzed Negishi r

应助信息

19小时前

Book学术机器人

0ec8edaa5be511f198b034735aa3bc31.pdf 已采纳

19小时前

Book学术机器人

2026/11/5 13:12:04 Book学术AI机器人已找到文献并上传

2026/11/5 13:12:04 Book学术AI机器人收到请求，开始寻找文献

2026/11/5 13:12:04 已向机器人发送请求

19小时前

fengpeng 发布求助

上一个求助:其它数据库Naturally Fractured Carbonate Reservoir Characterization: A Case Study of a Mature High-Pour Point Oil Field in Hungary 下一个求助:其它数据库DOUBLY NONLINEAR VOLTERRA EQUATIONS INVOLVING THE LERAY-LIONS OPERATORS