Conditionally Active CD28xVISTA Bispecific Antibodies Promote Myeloid-Driven T-cell Activation.

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DOI:10.1158/2326-6066.CIR-25-0535
作者：Thomas Thisted,?F Donelson Smith,?Zhi-Gang Jiang,?Zuzana Biesova,?Adejumoke M Onumajuru,?Yuliya Kleschenko,?Kanam Malhotra,?Vikas Saxena,?Arnab Mukherjee,?Edward H van der Horst
文献类型：期刊论文
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American Association for Cancer Research (AACR)

Abstract：Reinvigoration of tumor-reactive T cells using costimulatory bispecific antibodies (bsAb) targeting CD28 is emerging as a promising therapeutic strategy. Conditional, tumor-specific recruitm

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