Nose-to-Brain Delivery of mRNA-Loaded Lipid Nanoparticles Bypasses the Blood–Brain Barrier for Effective Brain Disease Therapy

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DOI:10.1021/acsnano.6c04580
作者：Xiaolu Yu, Xiao-Meng Deng, Yi Lin, Hongyu Ren, Lu Jia, Yanan Meng, Fan Liu, Qiang Cheng*, Zhao-Qian Teng* and Tuo Wei*, 
文献类型：期刊论文
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Abstract：mRNA-loaded lipid nanoparticles (mRNA-LNPs) show great therapeutic potential, but their use in central nervous system (CNS) disorders is limited by poor blood–brain barrier (BBB) penetration

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