Novel Conformational Polymorph and Mixed Solvates of Anti-tumor Drug Ripretinib: Selection of High Soluble and Stable Mixed Solvate

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DOI:10.1021/acs.cgd.6c00382
作者：Muthukumari Muthaiyan,?Anubha Srivastava and Palash Sanphui*,?
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Ripretinib (hereafter RIP) is an antitumor drug that is practically insoluble in water and belongs to the BCS class II category. In addition to the reported two polymorphs (Forms 1 and 2), a

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