DHRS9 generates crotonyl-CoA from butyryl-CoA to epigenetically regulate STING transcription and potentiate immune activation.

待确认 10 由 linuh 发布于 2026/11/12 22:06:20

DOI:10.1038/s41418-026-01819-1
作者：Yuling Zhang,?Fei Qin,?Jiajia Zhang,?Xuemei Bai,?Jiahua Yuan,?Nan Cao,?Na Dong,?Min Zhou,?Ziye He,?Xiaoxiao Li,?Huanming Wang,?Chengjiang Gao,?Bingyu Liu
文献类型：期刊论文
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Nature

Abstract：The stimulator of interferon genes (STING) pathway is a cornerstone of innate immunity and a promising therapeutic target for autoimmune diseases, inflammation, and cancer treatment. Lysine

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