Protein Abundance of Hydrolytic Drug Metabolizing Enzymes in Different Tissues and across Species

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DOI:10.1021/acs.jmedchem.6c00165
作者：Sandhya Subash, Deepak Ahire, Robert S. Jones, Bin Ma, Yu Tian, Ting Wang, S. Cyrus Khojasteh, Bernard P. Murray, David M. Stresser, Mitchell Taub and Bhag
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American Chemical Society (ACS)

Abstract：Hydrolytic drug-metabolizing enzymes (hydrolases) are essential for the metabolism of many therapeutic agents; however, comprehensive data on their tissue distribution and interspecies varia

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