MARCHF6 orchestrates hepatic lipid homeostasis by targeting SREBP1 for ER-associated degradation

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DOI:10.1016/j.jhep.2026.04.036
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1016/j.jhep.2026.04.036

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Abstract：•Hepatic MARCHF6 expression is markedly reduced in mouse models and human patients with MASLD.•Liver-specific deletion of Marchf6 aggravates hepatic steatosis, inflammation, and fibrosis.•MA

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