Efficient in vivo cytosine base editing using virus-like particles with uracil DNA glycosylase inhibition.

求助中 10 由闻发布于 2026/11/14 10:53:29

DOI:10.1038/s41587-026-03227-9
作者：Junjie Zhu,Lin Ding,Kai-Ming Liu,Xingyu Zhu,Jifang Li,Buer Ha,Bao-Qing Gao,Xujiao Zhou,Chengfang Liu,Jia Wei,Shuangyu Ma,Wenchao Xu,Lingyun Kong,Jing Wu,Xiaodun Mou,Bei Yang,Lijie Wang,Jiaxu Hong,Li Y
文献类型：期刊论文
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Nature

Abstract：Virus-like particles (VLPs) are promising for delivering genome editors, yet the in vivo in vivo efficacy of VLP-mediated cytosine base editing remains limited. Here we identified insufficie

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