Downregulating human leucocyte antigens on mesenchymal stromal cells by epigenetically repressing a β2-microglobulin super-enhancer

已完结 10 由 clm 发布于 2026/5/29 14:53:49

DOI:10.1038/s41551-024-01264-w
作者：Fei Wang,&nbsp;Ran Li,&nbsp;Jing Yi Xu,&nbsp;Xiaoxia Bai,&nbsp;Ying Wang,&nbsp;Xu Ri Chen,&nbsp;Chen Pan,&nbsp;Shen Chen,&nbsp;Ke Zhou,&nbsp;Boon Chin Heng,&nbs
文献类型：期刊论文
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Nature

Abstract：Immune rejection caused by mismatches in human leucocyte antigens (HLAs) remains a major obstacle to the success of allogeneic cell therapies. Current strategies for the generation of ‘unive

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