Gut microbiota metabolite Urolithin B inhibits chondrocyte ferroptosis by rewriting iron homeostasis via FGFR3/NCOA4/FTH1 axis, alleviating osteoarthritis

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DOI:10.1016/j.phymed.2025.157292
作者：Yanlin Li ,?Hanwen Gu ,?Xiaotian Jiang ,?Jiale Li ,?Qi Li ,?Kangle Song ,?Xiangzhen Kong ,?Qunbo Meng ,?Anhao Shi ,?Junhao Lin ,?Bin Chen ,?Gang Wang ,?Hong Zhang ,?Qingjia Xu
文献类型：期刊论文
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Elsevier

Abstract：BackgroundOsteoarthritis (OA) is a prevalent chronic disease characterized by articular cartilage degeneration. The lack of safe and effective therapies has made OA a leading global cause of

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