Lidocaine potentiates thermal ablation in cholangiocarcinoma by modulating TRPV6-Driven Ca2+/PI3K/AKT/HSF-1 signaling pathway

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DOI:10.1016/j.canlet.2025.218226
作者：Ping-ping Chen , Yun-kai Lin , Ming-xing Xia , Hui-bo Feng , Yu-fei Pan , Ye-xiong Tan , Meng-you Xu , Xin-hao Xing , Xiao-meng Yao , Bing Hu , Hong-y
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1016/j.canlet.2025.218226

Elsevier

Abstract：Sublethal heat stress during thermal ablation induces thermotolerance and tumor recurrence, limiting its efficacy in cholangiocarcinoma (CCA). Here, we reported that lidocaine, a commonly us

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