Combinatorial Engineering of the Catalytic Pocket and Structural Stability in 4-Vinylguaiacol Oxygenase for Efficient Vanillin Biosynthesis

已完结 20 由 xx 发布于 2026/10/27 11:05:46

DOI:10.1021/acs.jafc.6c00484
作者：Feng Yujie, Fan Lingxi, Wen Qifeng, Xu Xiangwei, He Qinghong, Fu Xiaofen, Liu Jinlong, Tian Jian, Yang Maohua, Xing Jianmin
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acs.jafc.6c00484
备注：合成生物学项目相关，感谢！

American Chemical Society (ACS)

Abstract：The low activity of 4-vinylguaiacol oxygenase severely limits the biocatalytic synthesis of vanillin from ferulic acid. In this study, strategies involving catalytic pocket engineering and m

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