BAK and BAX form a multiprotein complex to drive mtDNA efflux and caspase-independent cell death

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DOI:10.1126/science.aea2181
作者：Shaoyuan Yang, Hyungjin Kim, Guanghong Liao, Na Ta, Ho-Chou Tu, Shriram Ramani, Chih-Yu Chen, Zih-Yu Li, Nobuhiro Tanno, James J. Hsieh, Emily H. Chen
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：The apoptotic regulators BAX and BAK, once activated, form homo-oligomers to trigger mitochondrial outer membrane permeabilization (MOMP), activating the apoptosome and caspases. Activation

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