A gasdermin-based life–death evolution system for reprogramming protease specificity

已完结 10 由 gu 发布于 2026/10/28 15:10:32

DOI:10.1038/s41589-025-02063-3
作者：Ziqi Gao, Tianzhen Li, Hao Ye, William Shu Ching Ngai, Huijie Wang, Peng R. Chen, Jie Wang
文献类型：期刊论文
补充材料：只需要正文

Nature

Abstract：Reprogramming the specificity of proteases toward alternative target sequences could enable an array of exciting applications, ranging from proteome editing to therapeutic interventions. Her

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