Preclinical efficacy and pharmacokinetics of an RNA-encoded T cell–engaging bispecific antibody targeting human claudin 6

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DOI:10.1126/scitranslmed.adl2720
作者：Christiane R. Stadler, Ursula Ellinghaus, Leyla Fischer, Hayat B?hr-Mahmud, Martin Rao, Claudia Lindemann, Anuhar Chaturvedi, Caroline Scharf, Imke Biermann,&nb
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1126/scitranslmed.adl2720

American Association for the Advancement of Science (AAAS)

Abstract：We present the preclinical pharmacology of BNT142, a lipid nanoparticle (LNP)–formulated RNA (RNA-LNP) encoding a T cell–engaging bispecific antibody that monovalently binds the T cell marke

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