Mechanosensitive calcium channels and integrins coordinate the reprogramming of colorectal cancer cells into a fetal-like state.

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DOI:10.1016/j.celrep.2025.116308
作者：Mirjam C van der Net, Marjolein J Vliem, Lars J S Kemp, Carlos Perez-Gonzalez, Tariq S Haddad, Esther A Strating, Ana Krotenberg-Garcia, Ronja M Houtekamer, Wil
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Elsevier

Abstract：Colorectal cancer (CRC) cells exhibit high plasticity and transition between different cellular states during the development of metastasis. Lgr5-expressing cancer stem cells fuel the growth

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