A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer

已完结 10 由 w 发布于 2026/11/2 22:51:11

DOI:10.1101/2023.12.10.570854
作者：Slim Mzoughi, Megan Schwarz, Xuedi Wang, Deniz Demircioglu, Gulay Ulukaya, Kevin Mohammed, Federico Di Tullio, Carlos Company, Yuliia Dramaretska, Marc Leushacke, Bruno Giotti, Tamsin Lannagan, Daniel
文献类型：期刊论文
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Nature

Abstract：Targeting cancer stem cells (CSCs) is crucial for effective cancer treatment1. However, the molecular mechanisms underlying resistance to LGR5+ CSCs depletion in colorectal cancer (CRC)2,3 r

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