DNA-FISH Metaphase Spreads to Distinguish Extrachromosomal DNA from Homogeneously Staining Regions in Human Cancer Cell Lines.

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DOI:10.3791/71970
作者：Lauren Marie Masters,?Katelin Maria Hagstrom,?Graham Scott Erwin
文献类型：期刊论文
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Abstract：Whole-genome sequencing identifies focal DNA amplifications with base-pair resolution but cannot determine whether amplified sequences reside on extrachromosomal DNA (ecDNA, also known as do

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