Use of PBPK modelling to extrapolate in vitro porcine ear skin permeability to in vivo human dermal absorption

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DOI:10.1016/j.ijpharm.2025.126168
作者：Laura Krumpholz ,?Sebastian Polak ,?Barbara Wi?niowska
文献类型：期刊论文
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Elsevier

Abstract：Porcine ear skin is widely accepted as a surrogate for human skin in in vitro permeation tests (IVPT); however, differences in permeability between the two have been reported in several stud

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