Atlas of lysosomal aging reveals a metabolite signature shared with lysosomal storage disorders

已完结 10 由 HH 发布于 2026/8/14 16:32:43

DOI:10.1126/science.ady0832
作者：Anna M. Puszynska, Thao P. Nguyen, Andrew L. Cangelosi, Andrea Armani, Justin M. Roberts, Kristin A. Singh, James C. Cameron, Tenzin Tseyang, Grace Y. Liu,&nbsp
文献类型：期刊论文
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American Association for the Advancement of Science (AAAS)

Abstract：Lysosomal dysfunction is a well-recognized feature of aging. Here, we used a suite of tools for rapid lysosomal isolation to construct a multitissue atlas of the metabolite changes lysosomes

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