The USP1-WDR48 deubiquitinase complex functions as a molecular switch regulating tumor-associated macrophage activation and anti-tumor response

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DOI:10.1038/s41418-025-01548-x
作者：Dianwen Han,?Lijuan Wang,?Shan Jiang,?Peng Su,?Bing Chen,?Wenjing Zhao,?Tong Chen,?Ning Zhang,?Xiaolong Wang,?Yiran Liang,?Yaming Li,?Chen Li,?Xi Chen,?Dan Luo,?Qifeng Yang
文献类型：期刊论文
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Nature

Abstract：M2-like tumor-associated macrophages (TAMs) are the main immunosuppressive cells infiltrating the tumor microenvironment (TME), the activation of which is essential for cancer progression an

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