Discovery and Structure–Activity Relationship Studies of Diazepine Derivatives as a New Class of Ferroptosis Inhibitors with Potent Efficacy in the Doxorubicin-Induced Cardiomyopathy Model

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DOI:10.1021/acs.jmedchem.5c02855
作者：Jing You,?, ,?Lu Yang,?, ,?Yaru Qin,?, ,?Chenyu Tian,?, ,?Xin Yang,?, ,?Mingli Xiang*,?, ,?Linli Li*,?, and ,?Shengyong Yang*,?
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：Ferroptosis, a regulated form of cell death driven by iron-dependent lipid peroxidation, contributes to diverse pathological conditions. However, the clinical translation of ferroptosis inhi

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