Considerations for Starting Material Designation for Drug-Linkers in Antibody–Drug Conjugates

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DOI:10.1021/acs.oprd.3c00140
作者：Michael T. Jones*,?Olivier Dirat,?David A. Conlon,?Charles Melucci,?Kate Schrier,?Thomas Raglione,?Qunying Zhang and Paul G. Bulger,?
文献类型：期刊论文
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American Chemical Society (ACS)

Abstract：By combining the unique targeting ability of monoclonal antibodies with the cancer-killing ability of cytotoxins, antibody–drug conjugates (ADCs) exhibit unique properties that preclude them

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