A CRISPR activation screen identifies SPART as a pan-orthoflavivirus restriction factor.

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DOI:10.1016/j.chom.2026.04.018
作者：Qi Li,?Yong Yin,?Yixin Liu,?Xiaoxue Ding,?Xingchi Nie,?Zikai Zhao,?Rong Zhang,?Hongming Ma,?Wenjing Zhu,?Shengxian Xiang,?Hehao Ouyang,?Fei Yang,?Zibin Yang,?Yunchuan Li,?Jun Gu,?Mengjie Yang,?Dou Wan
文献类型：期刊论文
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Elsevier

Abstract：Orthoflaviviruses, including Zika (ZIKV), dengue, Japanese encephalitis, and West Nile viruses, cause diverse clinical syndromes and threaten human health. Identifying factors that inhibit o

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