Harnessing Senolytics and PARP Inhibition to Expand the Antitumor Activity of CDK4/6 Inhibitors in Prostate Cancer.

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DOI:10.1158/1535-7163.MCT-24-0903
作者：Julian Brandariz,?Lara de Llobet,?Victor Esquefa,?Daniel Aguilar,?Andrei Salca,?Sara Arce-Gallego,?Pablo Cresta Morgado,?Arnau Sole,?Laura Agundez,?Gisela Mir,?Natalia Castro,?Teresa Casals,?Anna Oliv
文献类型：期刊论文
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文献链接：https://doi.org/10.1158/1535-7163.MCT-24-0903

American Association for Cancer Research (AACR)

Abstract：Metastatic prostate cancer (mPC) is a lethal disease; most therapeutic options focus on androgen receptor signaling inhibition, but resistance eventually arises. Cyclin-dependent kinase 4 an

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