Zodasiran for cholesterol and triglyceride lowering in patients with hyperlipidemia: final report of phase 1 basket trial

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DOI:10.1038/s41591-026-04307-8
作者：Gerald F. Watts, Russell Scott, David Sullivan, John Baker, Peter Clifton, James Hamilton, Bruce Given, Stacey Melquist, Rong Zhou, Daniel Gaudet, Ira
文献类型：期刊论文
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Nature

Abstract：Loss-of-function variants in the gene encoding angiopoietin-like protein 3 (ANGPTL3) are associated with decreased triglyceride and low-density lipoprotein cholesterol levels, as well as wit

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