Advancing Peptide Synthesis: Liquid-Phase Assembly of Tirzepatide’s C-Terminus (30–39) via Crystalline Pentamer Building Blocks

已完结 10 由杨小木发布于 2026/8/4 13:47:11

DOI:10.1021/acs.oprd.5c00304
作者：Paridhi Agrawal, , , Mark R. Berglund, , , Emily Murzinski Valco, , , Jing Teng, , , Kevin D. Seibert, , and , Michael E. Kopach*, 
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acs.oprd.5c00304

American Chemical Society (ACS)

Abstract：Traditional solid-phase peptide synthesis (SPPS) is limited in its suitability for high-volume peptide/protein manufacturing applications due to its reliance on specialized equipment, high p

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