Design and synthesis of 4-substituted-8-(2-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one as a novel class of GlyT1 inhibitors: Achieving selectivity against the μ opioid and nociceptin/orphanin FQ peptide (NOP) receptors

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DOI:10.1016/j.bmcl.2006.05.064
文献类型：期刊论文
补充材料：仅需补充材料
文献链接：https://doi.org/10.1016/j.bmcl.2006.05.064

Elsevier

Abstract：A novel class of 4-substituted-8-(2-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-ones have been discovered and developed as potent and selective GlyT1 inhibitors. The molecules are devoid

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