Rifaximin ameliorates cirrhotic portal hypertension through suppression of microbiome-derived deoxycholic acid.

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DOI:10.1016/j.jhep.2026.05.001
作者：Hai-Lin Xiong, Qi Zhao, Shu-Qing Liu, Li-Lin Chen, Mei-Tong Nie, Xia-Lu Hong, Chen-Hong Ding, Ru Huang, Nan Jiang, Fei Chen, Yu-Hao Song, Xin Zha
文献类型：期刊论文
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Elsevier

Abstract：Background & aims: Microbiome-derived deoxycholic acid (DCA) elevates serum 5-hydroxytryptamine (5-HT), a mediator of portal hypertension (PH). Rifaximin, a non-absorbable antibiotic, is kno

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