Quantitation of non-derivatized free amino acids for detecting inborn errors of metabolism by incorporating mixed-mode chromatography with tandem mass spectrometry

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DOI:10.1016/j.jmsacl.2022.05.002
文献类型：期刊论文
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文献链接：https://doi.org/10.1016/j.jmsacl.2022.05.002

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Abstract：IntroductionAmino acids are critical biomarkers for many inborn errors of metabolism, but amino acid analysis is challenging due to the range of chemical properties inherent in these small m

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