Endocytic evasion confers resistance to antibody-drug conjugates therapy in cancer.

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DOI:10.1016/j.ccell.2026.04.010
作者：Yuzhao Wang, Zibin Chen, Weikai Wang, Lijuan Jiang, Xiaoyu Liang, Zhuowei Liu, Zikun Ma
文献类型：期刊论文
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Elsevier

Abstract：Enfortumab vedotin (NECTIN4-ADC), a NECTIN4-targeting antibody-drug conjugate, has shown substantial efficacy in urothelial carcinoma, yet primary and acquired resistance remain major barrie

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