Mechanism of Nucleic Acid Phosphodiester Bond Cleavage by Human Endonuclease V: MD and QM/MM Calculations Reveal a Versatile Metal Dependence.

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DOI:10.1021/acs.jpcb.4c05846
文献类型：期刊论文
补充材料：只需要正文
文献链接：https://doi.org/10.1021/acs.jpcb.4c05846

American Chemical Society (ACS)

Abstract：Human endonuclease V (EndoV) catalytically removes deaminated nucleobases by cleaving the phosphodiester bond as part of RNA metabolism. Despite being implicated in several diseases (cancers

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