Rapid Construction of a Tyr C6–Trp C5′ Linkage: Application in the Total Synthesis of Micitide 982, a Noncanonical Cyclic Peptide

已完结 20 由再说发布于 2026/8/11 14:34:43

DOI:10.1002/ange.202516053
作者：Hiroshige Ogawa,?Prof. Dr. Yuuya Nagata,?Tsz Ki Chan,?Prof. Dr. Yudai Matsuda,?Prof. Dr. Hugh Nakamura
文献类型：期刊论文
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Wiley

Abstract：In this study, a facile synthesis method for a highly strained Tyr C6-to-Trp C5′ linkage was developed. This method enables the convergent introduction of arbitrary biaryls to peptide linker

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