Rational design of DXd derivatives for liposomal drug delivery: Towards safer and more effective cancer treatments

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DOI:10.1016/j.ijpharm.2025.125688
作者：Jinbo Li ,?Jiang Yu ,?Baoyue Zhang ,?Jia Song ,?Ruiping Huang ,?Ning Li ,?Yingxi Zhang ,?Shuang Zhou ,?Xin Li ,?Zhonggui He ,?Hongzhuo Liu ,?Yongjun Wang
文献类型：期刊论文
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Elsevier

Abstract：DXd (Exatecan derivative), a novel TOPO-I inhibitor, exhibits high membrane permeability and an efficient bystander effect, serving as a critical cytotoxic drug component in antibody-drug co

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