Progranulin deficiency-induced lysosomal dysfunction drives maladaptive myeloid cell states through the MITF/TFE transcription factors

已完结 10 由 OM 发布于 2026/8/12 9:19:15

DOI:10.1016/j.immuni.2026.07.009
作者：Leon Tejwani,Catherine M. Heffner,Christopher Balak,Lukas L. Skuja,David Tatarakis,Anil Rana,Seungyoon B. Yu,Gabriel A. Fitzgerald,Connie Ha,Gabrielly Lunkes de Melo,Elizabeth W. Sun,Matthew J. Simon,
文献类型：期刊论文
补充材料：只需要正文

Elsevier

Abstract：Lysosomal dysfunction in myeloid cells is increasingly implicated in neurodegenerative diseases. To examine the interplay between lysosomal health and cellular state, we performed multi-omic

应助信息

求助已完结，文件已删除 如有需求请重新发布求助一键发布

感谢使用Book学术
本站所有文献仅供个人学习和参考，请勿将文件进行传播。共同遵守网站规定和相关知识产权规定。

上一个求助:其它数据库Naturally Fractured Carbonate Reservoir Characterization: A Case Study of a Mature High-Pour Point Oil Field in Hungary 下一个求助:American Chemical Society (ACS)Tellurophene-Tagged Carfilzomib Enables Single-Cell Mass Cytometric Mapping of Proteasome Activity